Antihyperglycemic Activities of Uli Banana Leaves on Oral Sugar Tolerance

  • Phebe Hendra Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Sanata Dharma University, Jogjakarta, 55282, Indonesia
  • Nona Rizki Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Sanata Dharma University, Jogjakarta, 55282, Indonesia
  • Elin Nidia Safitri Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Sanata Dharma University, Jogjakarta, 55282, Indonesia
Keywords: antihyperglycemic, glucose, leaves, sucrose, uli banana

Abstract

Banana has been widely cultivated. This study aimed to determine the antihyperglycemic activity of Uli banana leaves infusion. The antihyperglycemic activity was evaluated by oral glucose and sucrose tolerance test. A bolus of sugar was given after Uli banana leaves infusion and blood was sampled at 0, 15, 30, 60, 90 and 120 minutes for glucose analyses. The trapezoidal rule was used to determine the area under the curve (AUC) blood glucose. Infusion of Uli banana leaves 3.3 g/kg showed a significant decrease AUC (p<0.05) in the glucose tolerance test, while that of dose 0.8 g/kg reduced significantly (p<0.05) in the sucrose tolerance test. The results showed that Uli banana leaves infusion possesses antihyperglycemic effect in mice.

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Published
2021-02-17
How to Cite
Hendra, P., Rizki, N., & Safitri , E. (2021). Antihyperglycemic Activities of Uli Banana Leaves on Oral Sugar Tolerance. Journal of Functional Food and Nutraceutical, 2(2), 75-79. https://doi.org/10.33555/jffn.v2i2.59
Section
Short Communications and Notes